QIIME: Quantitative Insights Into Microbial Ecology
http://www.qiime.org

QIIME Allows Integration and Analysis of High-Throughput Community Sequencing Data
J. Gregory Caporaso, Justin Kuczynski, Jesse Stombaugh, Kyle Bittinger, Frederic D. Bushman, Elizabeth K. Costello, Noah Fierer, Antonio Gonzalez Pena, Julia K. Goodrich, Jeffrey I. Gordon, Gavin A. Huttley, Scott T. Kelley, Dan Knights, Jeremy E. Koenig, Ruth E. Ley, Cathy A. Lozupone, Daniel McDonald, Brian D. Muegge, Meg Pirrung, Jens Reeder, Joel R. Sevinsky, Peter J. Turnbaugh, William van Treuren, William A. Walters, Jeremy Widmann, Tanya Yatsunenko, Jesse Zaneveld and Rob Knight. 
Nature Methods, 2010.